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Patient At Weill Cornell Medical Center Cured Of HIV Using Variation On Bone Marrow Transplant – CBS New York

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February 19, 2022
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Patient At Weill Cornell Medical Center Cured Of HIV Using Variation On Bone Marrow Transplant – CBS New York
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NEW YORK (CBSNewYork) — For less than the third time ever, an individual has been cured of their HIV an infection.

It took a variation on a bone marrow transplant utilizing umbilical twine blood. As CBS2’s Dr. Max Gomez experiences, this growth might open up the potential of a remedy to extra folks of various racial backgrounds.

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Amazingly, about 1% of individuals of European descent have a genetic mutation that forestalls them from making a receptor that HIV must be ingested into immune cells to do its soiled work. These individuals are successfully proof against HIV.

So if an individual had been to get a bone marrow transplant from a type of genetically immune donors, they too can be immune to HIV. That’s what has been performed in two sufferers with leukemia, however…

“The individuals who have been cured from HIV have been individuals who’ve had leukemia, who’ve required these harmful kinds of procedures, high-intensity chemotherapy, to get rid of their very own immune system in order that they will settle for a transplant that has the mutation, that has the profit additionally of resisting HIV,” mentioned Dr. Bruce Hirsch, with Northwell Well being.

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Now, a 3rd leukemia affected person has been cured of their HIV, however this time utilizing stem cells from umbilical twine blood. The process, performed at NewYork-Presbyterian/Weill Cornell Medical Center, is safer, extra broadly out there than stem cells from bone marrow and doesn’t must be as intently matched to the recipient.

Nonetheless, Hirsch, who treats HIV sufferers, says this isn’t a remedy for HIV or AIDS.

“That is useful, however this isn’t the foremost breakthrough that’s going to alter the face of HIV,” he mentioned.

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Along with being a dangerous process, stem cell transplants are very costly, plus there’s the problem of discovering these 1% of donors who’re genetically immune to HIV.



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Tags: BoneCBSCenterCornellCuredHIVMarrowMedicalpatientTransplantVariationWeillYork
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